There is a large individualized variation in how often seizures occur, and some patients may have one seizure for life, while others may have several seizures a day. Epilepsy is a clinical syndrome caused by highly synchronized abnormal discharges of neurons in the brain due to multiple causes, and its manifestations are seizure-like, transient, repetitive, and stereotypical. The probability of having one to several occasional seizures in a person’s lifetime is as high as 5%, and 39% of people with epilepsy have a tendency to spontaneous remission. Therefore, how often a person with epilepsy has seizures needs to be specifically analyzed in relation to the patient’s specific etiology, lesion size, and treatment. In addition, not every epilepsy patient needs medication. Generally speaking, those who have more than two seizures within six months can apply antiepileptic drugs after a clear diagnosis. If a person has one seizure for the first time or more than six months apart, he or she can be informed of the adverse drug reactions and the possible consequences without treatment and be selected at his or her discretion.