Acne generally refers to acne, which is a chronic inflammatory disease of the sebaceous glands of the hair follicles, in which the patient’s skin develops pimples and papules, etc., and is most commonly found on the face. Acne may be associated with abnormal androgen levels, excessive sebum secretion, and abnormal keratinization of cells around the hair follicles. 1. Abnormal androgen levels: Increased levels of androgens in the body can cause the sebaceous glands to produce more oil, which can clog pores and lead to acne on both sides of the cheeks and chin. 2. Excessive oil secretion: If you have recently consumed too much oily food or have oily skin, you may have excessive sebaceous gland secretion on both sides of your cheeks and chin, which can clog your pores and cause acne. 3. Abnormal keratinization of the cells around the hair follicles: If the cells around the hair follicles on both sides of the cheeks and chin are abnormally keratinized, the opening of the hair follicles may be narrowed and clogged, which prevents sebum from being discharged normally and triggers bacterial infections, ultimately leading to the formation of acne. There are many factors that can cause acne on both sides of the cheeks and chin, and patients need to pay attention to skin care, cleanliness, and consume more fresh fruits and vegetables. It is also recommended to go to the hospital to clarify the cause of acne.