Patients with penicillin anaphylaxis, the main rescue measures are as follows: 1, must immediately stop the infusion of penicillin, discard the original infusion set, replace the infusion set, use 0.9% saline to give intravenous drip.2, general treatment usually must make the patient lying down or semi-sitting position, give static. In addition, cardiac monitoring can be given to monitor vital signs, oxygen. 3, the establishment of multiple venous channels, speed up the rehydration, expansion of blood volume, to correct the shock. 4, can be applied to targeted drugs, the most commonly used is epinephrine, usually with epinephrine 0.5mg given intramuscularly, can be applied to the application of anti-allergic drugs, commonly used intramuscular injection of benzydamine. 5, can be applied to the application of glucocorticoid-like Glucocorticoid drugs can be applied by intravenous drip or push, commonly used is methylprednisolone or dexamethasone.