Body fatigue and tiredness, this time the first should be clear cause, according to the different causes of the corresponding drug treatment, the common causes are diabetes, hypothyroidism, menopausal syndrome and other diseases. 1. Diabetes. Diabetes mellitus can cause the above symptoms, and accompanied by drinking, eating and losing weight, etc., then you can apply anti-diabetic drugs for treatment, commonly used drugs are glimepiride tablets, metformin extended-release tablets, etc., and the cause of diabetes mellitus can be determined according to different causes. 2. Hypothyroidism can cause the above symptoms, accompanied by poor appetite, fear of cold and other symptoms. Antihypothyroidism drugs can be used for treatment, such as thyroxine tablets. 3. Menopause syndrome. Menopausal syndrome can have the above symptoms and accompanied by insomnia, depression and so on. At this time, you can apply Kun Bao Pills and other drugs to improve the symptoms. Therefore, if you are physically tired and fatigued, you can get a better result if you do the above treatment after clarifying the cause of the disease.