Gastric cancer tissue erosion reaches the plasma membrane layer and cancerous nodules are seen, which can be treated by surgery, radiotherapy, targeted therapy and other methods. Gastric cancer is a common malignant tumor of the digestive system, which can be caused by Helicobacter pylori infection, heredity and other factors. After examination, gastric cancer tissue erosion reaches the plasma membrane layer and cancerous nodules are seen, and combined with lymph node metastasis and whether distant metastasis occurs, it can be staged from II to IV. For stage II and III, which are relatively early, if there is a chance of surgery, surgical resection is feasible, followed by radiotherapy and chemotherapy; while for stage IV, there is no chance of surgery, and non-surgical therapies such as radiotherapy and targeted therapy are feasible. Patients do not need to panic too much, and actively cooperate with the doctor’s treatment.