Pancreatic tail flaky low density foci refers to the patient did abdominal ct, in the tail of the pancreas found in the flaky lower than the density of pancreatic organs foci, most commonly seen in pancreatic pseudocysts, pancreatic cystic tumor, pancreatic abscess or pancreatic cancer and other diseases. 1. Pancreatic pseudocyst: it is the most common cystic lesion of the pancreas, mostly secondary to leakage and accumulation of pancreatic fluid caused by acute and chronic pancreatitis, and then form cysts after being wrapped by the surrounding tissues and organs. If the volume is large, it can produce compression symptoms, secondary infection and abscess formation, etc. It can be seen as flaky low density foci in the tail of the pancreas. 2. Pancreatic cystic tumor: mostly seen in middle-aged and old women, most of them are asymptomatic, but may have symptoms of compression, epigastric pain and discomfort, or abdominal swelling, etc. It can be seen as flaky low-density foci in the tail of the pancreas. Diagnosis mainly relies on imaging tests, including CT and MRI, and it is difficult to identify benign and malignant, and biopsy can be taken to identify benign and malignant. 3. Pancreatic abscess: generally secondary to pancreatic pseudocyst, peripancreatic fluid infection can occur. Symptoms are fever, abdominal pain, etc. The tail of the pancreas can be seen as a flaky low-density focus. 4. Pancreatic cancer: low-density foci do not exclude pancreatic cancer. Epigastric pain, discomfort as the first symptom, jaundice as the main symptom of the clinical manifestations, can be seen in the tail of the pancreas flaky low density foci. CA19-9 can be checked for differential diagnosis. Specific diagnosis also need to go to the regular hospital, comprehensive diagnosis, follow the doctor’s advice, early treatment.