Osteomalacia is caused by degenerative changes, and the pain is related to the stimulation of surrounding tissues or compression of nerves. The treatment is mainly divided into general treatment, physiotherapy, drug treatment and surgery, etc., which need to be targeted according to the location of the hyperplasia and the degree of pain. 1. General treatment: if pain is caused by osteophytes, avoid excessive weight-bearing activities, reduce weight, correct bad posture, pay attention to warmth, you can take bicycling, swimming and other ways of exercise, which is helpful for relieving pain. 2. Physiotherapy: Commonly used methods include ultra-short wave, infrared moxibustion, wax therapy, intermediate frequency, etc., which can relieve muscle spasm in the growth area, improve blood circulation, and reduce pain symptoms. 3. Medication: If the pain of osteophytes is more obvious, you can take non-steroidal painkillers orally for auxiliary treatment, such as diclofenac sodium enteric-coated tablets, ibuprofen extended-release capsules, etc., and you can also cooperate with anti-osteoporosis pills, glucosamine capsules and other medicines, which are effective in pain caused by osteophytes. 4. Surgery: If the pain caused by osteophytes is ineffective through active conservative treatment, surgery can be considered. For example, if the osteophytes are caused by the knee joint, artificial knee joint replacement can be taken, and the pain caused by severe lumbar spondylolisthesis can be fixed with intervertebral implantation and fusion of the vertebral plate decompression. When osteophytes caused by pain, can be improved by keeping warm and active exercise, if the pain progressive aggravation, should be timely consultation, by the doctor to develop individualized program for targeted treatment, do not blindly use drugs.