Sore ankles after playing soccer should be treated with general therapy, medication, etc. depending on the cause. Common causes include exertion, soft tissue injury, traumatic synovitis and so on. 1. Exhaustion: During the process of playing ball, the ankle joint area is subjected to the most force, which causes the accumulation of lactic acid and leads to the soreness of the ankle area. You can rest more and reduce activities. 2. Soft tissue injury: when playing ball, the muscles, ligaments, fascia, tendons and so on around the ankle joint are pulled for a long time, resulting in congestion, edema and pain, oral ibuprofen extended-release capsules can be taken to reduce inflammation and relieve pain. 3. Traumatic synovitis: overuse or improper use of the ankle joint, causing synovial membrane damage, rupture, etc., triggering ankle pain. It is recommended to take oral Loxoprofen sodium tablets to relieve fever, analgesia and anti-inflammation. There may be other reasons for sore ankles after playing soccer, it is recommended to go to the hospital in time, the above medication needs to be under the guidance of a doctor, avoid taking medication on your own.