Causes of Alzheimer’s disease Genetic and psychosocial factors are the two main factors, with the former being the most prominent. A parent or brother with Alzheimer’s disease is four times more likely to develop Alzheimer’s disease themselves than those without a family history. Studies have also revealed the influence of psychosocial factors on Alzheimer’s disease, with low education ranked first among more than 100 psychosocial factors, and the age of onset can be delayed by 7 to 10 years for those with formal education compared to those with no education. In addition, psychosocial factors such as low occupation, low cognitive function, widowhood and non-remarriage, and non-participation in social activities also predispose to Alzheimer’s disease. Symptoms of Alzheimer’s disease 1, memory impairment recent memory loss, can not remember the recent events, and later forget the past events, in serious cases, even the names of family members, their own age do not know, and even appear gibberish. 2, thinking and judgment difficulties thinking poor, lack of creativity, comprehensive analysis ability is reduced, can not distinguish priorities, and even can not understand the basic common sense. The ability of daily life is diminished, and the person is not able to perform the work he or she was familiar with. 3, language disorder in spontaneous speech, obvious word finding difficulty is the first manifestation of language disorder. This is followed by an inability to name common objects and names of friends, or a mispronunciation at the same time. 4.Orientation disorder has a disorder of orientation to time and place, not knowing what day it is, where they are now, and often get lost when they go out. 5.Personality and behavior abnormalities personality changes are manifested as becoming selfish, narrow-minded, and cold-hearted to others. 6, emotional indifference, behavioral withdrawal, lack of interest, will decline, no initiative and aggressiveness, inattentive or become impatient, suspicious, stubborn, irritable and impulsive. 7. Behavioral abnormalities manifest as sitting all day, becoming unkempt, living a lazy life or going out without purpose, wandering the streets, and disturbing family members’ rest by making noise at night for no reason. The signs and symptoms of Alzheimer’s disease may vary from person to person, and its course can be roughly divided into three stages. In the early stages, memory loss, reduced ability to work, loss of concentration, inability to remember what you have just walked, emotional instability, irritability, increased aggression, loss of interest in daily activities, but still maintaining the ability to live independently. In the middle stage, memory decreases severely, unable to do the work, can hardly remember the recent events, forget the meal just eaten, can’t even remember the year, month and day, can’t even recall the major events in life, judgment, comprehension and calculation are significantly reduced, in severe cases, don’t recognize friends or even relatives, or walk around aimlessly or pick up waste, and have inflexible limb activities. Patients can take care of themselves except for eating, dressing and urinating and defecating, but they rely on others to help them with the rest of their lives. Brain atrophy can be detected on cranial CT examination and increased slow waves can be seen on EEG. In the late stage, dementia is extremely obvious, with dull and indifferent expressions, bed-ridden, unable to carry out normal conversation, fragmented language, some walking unsteadily, falling to the east or limb contracture. Patients are completely unable to take care of themselves. Extensive cerebral atrophy was detected on cranial CT, and a comprehensive slow wave was seen on EEG.