Radiofrequency knife, also known as “stereotactic radiofrequency surgery platform”, also known as “network knife” or “computer knife”, is the world’s latest whole-body stereotactic radiosurgery treatment equipment. It can treat tumors in all parts of the body and can kill tumor tissues with only one to five irradiations. It is the only form of whole-body radiosurgery with the advantages of “no wound, no pain, no bleeding, no anesthesia and short recovery period”. It is the only radiosurgery device in the history of medicine that can treat intracranial and whole body tumors with a precision of less than 1mm and does not require nails to fix the head frame, which is a great breakthrough in the field of tumor treatment. Features: The technical core of the radio wave knife is interactive robotics, an integrated system that continuously receives feedback on patient position, tumor location and patient respiratory motion. Based on the feedback, the radio wave knife automatically and continuously positions each treatment beam with less than micron-level precision. Specifically, it has several outstanding features as follows. 1.Synchronous tumor tracking In some patients, the tumor will move with the breathing movement. At this time, the radio wave knife can use cruise missile satellite positioning technology to track the trajectory of the tumor at different points in time, and then instruct the robot arm to move simultaneously with the tumor movement to ensure that the gas pedal is always aligned with the tumor during irradiation, minimizing the damage to normal tissues. 2.Flexible robot arm In terms of appearance, the most important feature of the radio wave knife is that it has a precise and flexible robot arm. This precision robot arm with 6 degrees of freedom provides the best spatial expandability and mobility for treatment. It can have as many as 1200 beams in different directions, so that the irradiation dose can be delivered to lesions all over the body, truly realizing irradiation from any angle, which not only greatly reduces the damage to normal tissues and important organs around the tumor, but also effectively reduces the occurrence of radiation complications. 3.Simultaneous treatment of multiple tumors The radio wave knife has thousands of incident beams, which can arrange multiple tumor “surgeries” in the same treatment plan, and simultaneously treat different parts of the tumor that are not adjacent to each other. Of course, it can also treat irregularly located tumors and irregularly shaped tumors, and early tumors less than 6 cm can be completely eliminated. The flexible and accurate treatment characteristics of the radio wave knife enable it to treat intracranial injuries that are difficult to access with conventional equipment, such as meningioma, nasopharyngeal carcinoma, etc. Thus, the radio wave knife can treat tumors in most organs and tissues throughout the body. In addition, because the treatment process is non-invasive, non-bleeding, non-painful, and does not require anesthesia, there is no need for anesthesia recovery time after the “surgery” is completed, and the outpatient treatment mode greatly facilitates patients. Compared with general surgery, the patient’s recovery period after treatment is also significantly shorter. It is the only system that uses the human skeleton structure as the reference point for target positioning, and the only automated stereotactic radiation therapy system that can cure spinal and spinal cord injuries. 4.The whole process of painless treatment When treating tumors near the skull and spine, the radio wave knife adopts image-guided technology and uses bony markings on the skull or spine to achieve precise positioning of the patient’s location and completely realize non-invasive treatment. For tumors in the body, such as tumors in the lungs that are greatly affected by respiratory movements, the respiratory tracking technology is used to track and kill tumor cells in real time and precisely. 5.Applicable patient types The radio wave knife is mainly applicable to tumors growing near tissues that are sensitive to radiation; tumors with complex shapes; tumors that have no effect after other radiotherapy irradiation; tumors that recur after surgery; tumors that are difficult to be removed by surgery; patients whose bodies are too weak for surgical treatment; patients with other diseases that cannot be treated surgically; and patients who refuse surgical operation. 6.Clinical indications of radio wave knife What are the clinical indications of radio wave knife? Intracranial lesions: glioblastoma multiforme, malignant tumor, metastatic tumor, benign tumor, paraneoplastic tumor, auditory neuroma, pituitary adenoma, pediatric brain tumor, arteriovenous malformation, trigeminal neuralgia; spinal cord vertebral lesions: malignant tumor of spinal cord, metastatic tumor of spinal cord, benign tumor of spinal cord, benign tumor of vertebral bone, arteriovenous malformation of spinal cord; head and neck tumors: nasopharyngeal tumor, orbital tumor, primary head and neck tumor, primary tumor of spinal cord, primary tumor of spinal cord. primary head and neck tumors, malignant fibrous histiocytoma, cervical choroidal tumors; thoracic tumors: early non-small cell lung tumors, lung tumors in the hilar region, metastatic tumors of the lung, esophageal tumors, mediastinal tumors; abdominal tumors: primary tumors of the liver, metastatic tumors of the liver, pancreatic tumors, renal tumors, adrenal metastases, para-aortic lymphatic tumors, abdominal wall metastases; pelvic tumors: cervical tumors, prostate pelvic tumors: cervical tumors, prostate tumors, rectal and colon metastases, pelvic recurrent tumors; various sarcomas. Radiofrequency knife can treat not only micro tumors, but also larger tumors over 4CM, and there have been many successful treatment cases outside the United States. Although radio wave knife treatment is non-invasive, non-bleeding and non-anesthetic, it will more or less damage normal tissues, for example, after irradiation of lung cancer patients, the tumor area and tumor next to perhaps 0.5cm or 1cm will be irradiated with a relatively large dose, and the tissues in this area will be fibrotic. Of course, the doctor must judge whether the patient can tolerate the treatment and whether the damage will have a great impact on the patient’s life, if it has a particularly great impact or catastrophic consequences, the patient should not receive such treatment. Therefore, in the use of high-end technology products at the same time, the application of the same technology, experience is a test. Although the scope of treatment of radio wave knife is wide and many tumors can be treated with radio wave knife, except for digestive tract tumors, such as esophageal cancer and intestinal cancer, which are generally not suitable for radio wave knife treatment, because large doses of irradiation may cause perforation or ulceration of such tumors, and the consequences are very serious, so generally digestive tract tumors are not treated with radio wave knife. Therefore, radiofrequency knife is not used for digestive tumors. 11.The global application of radiofrequency knife treatment Currently, radiofrequency knife technology has been applied in about 100,000 tumor cases worldwide, and the treatment effect is remarkable. Today, more than 200 hospitals around the world have this expensive treatment equipment, two-thirds of which are American hospitals. The latest development of the radio wave knife tracking software provides patients with non-gold standard, non-invasive stereotactic image guidance technology for automatic tracking of static and respiratory tumors in the spine/spinal cord and lung. Its rapid six-dimensional image matching is fully integrated with the intelligent dynamic irradiation and real-time correction of the radio wave knife x-ray beam to achieve treatment accuracy of <0.75 mm for spinal lesions and <1.5 mm for lung lesions. Improving treatment effectiveness and avoiding normal tissue irradiation injury, thus reducing radiosurgery complications. Although conventional radiotherapy and radiofrequency knife use the same radiation source - 6MV high-energy X-rays, they are both radiation therapy. However, due to the unique design of the radio wave knife, such as flexible robotic arm, delicate gas pedal, precise 6-dimensional treatment bed, real-time image-guided positioning and image tracking, and simultaneous respiratory tracking, the characteristics of the radio wave knife exceed those of conventional gas pedals and reach the height of radiosurgery.