Heartburn on sildenafil may be related to inappropriate use of medication, adverse reactions and other factors, and should be promptly intervened with general treatment, change of medication and other treatments. 1. Improper use of drugs: If the drug is taken on an empty stomach, the drug may stimulate the gastric mucosa and cause heartburn. In this case, we should increase water intake to reduce the stimulation of gastric mucosa. At the same time, you should correct the bad habit of medication, which can effectively avoid the reappearance of this symptom. 2. Adverse reactions: after using the drug, some patients may have heartburn, nausea and other adverse reactions, you can consult a doctor in a timely manner, and follow the doctor’s instructions to adjust the dosage of the drug or replace other drugs such as tadalafil for treatment. 3. Other factors: such as reflux esophagitis and other diseases, can also trigger the symptoms of heartburn, should be timely compliance with the doctor’s instructions to apply omeprazole, aluminum thioglycollate and other drugs for treatment. The corresponding medication program, must follow the doctor’s instructions. After the use of drugs, constipation, skin rash and other adverse reactions, should also promptly seek medical help. After taking sildenafil, the symptoms of heartburn should be taken seriously, and medical treatment should be sought as soon as possible.