Ibuprofen may cause allergic reactions such as rashes, asthma exacerbation, increased risk of stomach bleeding, increased risk of heart attack and stroke and should be used under medical supervision. Ibuprofen is a non-steroidal anti-inflammatory drug that inhibits prostaglandin synthesis and has analgesic, antipyretic, and anti-inflammatory effects. It can be used to relieve mild to moderate pain such as arthralgia, neuralgia, migraine, and menstrual cramps, and can also be used to relieve fever caused by colds. Allergic reactions such as rash, facial swelling, asthma exacerbation and even anaphylaxis may occur with ibuprofen use. It may also cause stomach bleeding, especially in people over 60 years of age, patients with stomach ulcers, patients who are taking anticoagulants or steroids, and those who drink large amounts of alcohol over a long period of time. Ibuprofen can also increase the risk of heart attack, heart failure and stroke. Ibuprofen is contraindicated in people with a history of allergy to NSAIDs and should not be used before or after heart surgery. Ibuprofen should be used under a doctor’s supervision and the dose should not be increased arbitrarily. If discomfort occurs, you should seek immediate medical attention.