It is better not to take hepatitis B vaccine during menstruation, although menstruation is a normal physiological period for women, but the resistance of the body relatively decreases at this time, if you take hepatitis B vaccine during the period of decreasing resistance, the hepatitis B vaccine itself has a certain degree of toxicity, so it is recommended to take the hepatitis B vaccine after the menstruation is completely cleaned up, and before you take the vaccine, you should go through the laboratory test to know the two halves of hepatitis B. Based on the result, you can decide whether you can take the vaccine or not. The results of this test will determine whether the vaccine can be given. During menstruation, you should pay attention to both medication and diet, because some medications, such as blood-activating medications and medications for rheumatism, may lead to an increase in menstrual flow, so you have to pay special attention to the use of medication during menstruation. In addition, if you eat cold food during menstruation, it may lead to dysmenorrhea. So although menstruation is a normal physiological period, it may cause corresponding consequences if you don’t pay attention to it, so it is not recommended to take Hepatitis B vaccine during menstruation.