Increased AFP may or may not be an early manifestation of liver cancer, and further imaging and pathology tests are needed to clarify the cause. AFP is alpha-fetoprotein, which is mainly synthesized by the liver and yolk sac in the early fetal period, and its synthesis is suppressed soon after birth. It can be reactivated when liver cells or embryonic gonadal tissues develop malignant lesions, which can manifest as elevated AFP. Elevated AFP can be seen in the early stage of hepatocellular carcinoma, but it can also be seen in embryonic tumors of the gonads, such as testicular cancer, ovarian cancer, teratoma, etc. In addition, viral hepatitis, cirrhosis of the liver, as well as female pregnancy can also show elevated AFP. It is recommended that patients with elevated AFP should actively consult the doctor and improve CT and other imaging and pathologic examinations in order to clarify whether it is hepatocellular carcinoma.