Patient Question: Since my grandmother and grandmother are close sisters and my parents are related by cousins, I am a child of a consanguineous marriage. Marriage between close relatives can be bad for children, and I have been hesitant whether I should marry my daughter-in-law and whether it will be bad for children after marriage. At present, I want to go to the hospital to do some examination in related aspects, I don’t know what number to register, and I want to see if I can marry and have offspring. Treatment: No major problems were found during the unit’s physical examination. Medical history: No major problems since childhood. I want to go to the hospital for some related examinations, but I don’t know what number to register, and I want to see if I can get married and have offspring. Please give me some advice. Thank you! Doctor: The offspring of consanguineous marriages have an increased risk of developing recessive genetic diseases. However, if the offspring of a consanguineous marriage do not have a disease and are not related to the person they are married to, the risk of their offspring developing the disease is the same as that of other people. This means that as long as you and your loved one are not consanguineous, then you are part of the normal population, and the offspring of normal population marriages can have deformities, including mental retardation. This is a risk that all people who get married and have children face, you just need to follow the normal prenatal checkups like everyone else. For more detailed information, you can visit a genetic counseling clinic at the hospital.