Got coronary heart disease diabetes heart failure generalized swelling is mainly caused by heart failure, generally take diuretics, cardiac stimulants, hypoglycemic drugs treatment. 1. Diuretics: commonly used is hydrochlorothiazide, can also take torasemide, furosemide, etc., can promote urination, reduce the burden on the heart. 2. Cardiotonic agents: also known as positive inotropic drugs, such as digoxin, sildenafil, etc., can enhance the contraction capacity of the heart muscle, prevention and treatment of heart failure. 3. Hypoglycemic drugs: e.g. glibenclamide, gliclazide, some patients may need to take insulin injections to control their blood sugar level. All of the above medications need to be taken under the guidance of a doctor and should not be taken at random. With coronary heart disease diabetes heart failure generalized swelling, be sure to go to the hospital in a timely manner, with the doctor to take treatment.