16-year-old girl constipation is very serious, you can through the life of dietary regulation, abdominal massage and abdominal rubbing, medication and other methods to regulate. 1. Life and diet: change bad habits, develop the habit of regular defecation; pay more attention to water, do not eat spicy stimulation greasy food, eat more vegetables and fruits rich in dietary fiber, such as corn, celery, cabbage, bananas and so on. 2. Appropriate exercise to improve gastrointestinal power: reasonable and proper exercise can play a role in relieving constipation, such as walking slowly after meals. 3. medication: you can take probiotic drugs to regulate intestinal flora, such as lactobacillus tablets, bifidobacteria triple live bacteria, etc.; taking laxatives, such as polyethylene glycol, mannitol, etc.; you can use external corkscrew medication, which can stimulate rectum to promote defecation. These drugs exist in different degrees of adverse reactions, in the use of these drugs, must be strictly in accordance with medical advice under the guidance of a doctor.