Gout disease itself does not affect a patient’s fertility, but drugs such as colchicine and non-steroidal anti-inflammatory drugs (NSAIDs) used during gout treatment may have teratogenic and other effects. Gout is a common metabolic disease in daily life, which may be caused by enzyme and metabolic defects, diseases, drugs, excessive production of uric acid or reduced excretion of uric acid, etc., and can cause patients to experience severe pain in the joints, redness and swelling of the joints, etc. The disease itself does not have a close relationship with the reproductive system, and therefore does not directly affect the fertility of patients. Colchicine is commonly used during the acute attack of gout, the drug has a strong teratogenic effect, is strictly prohibited for use by pregnant and lactating women, in addition, ibuprofen, celecoxib and other non-steroidal anti-inflammatory drugs are also prohibited for use by pregnant and lactating women, gout patients with pregnancy should consult a physician to limit the use of the corresponding drugs. It is recommended that gout patients go to the rheumatology and immunology departments of regular hospitals for detailed consultation.