It is possible to live 20 years with colon cancer. Colon is the part of intestines in human body, and the occurrence of malignant tumor lesions is caused by the abnormal proliferation and differentiation of cells in colon; for colon cancer patients in early stage of development, if the lesion is confined to the part of colon, and there is no metastasis and spreading of tumor cells, then the patients can get a good prognosis after surgery, and they can possibly survive for 20 years. As a matter of fact, the survival time of colon cancer patients mainly depends on the pathological stage and the treatment method adopted by them; in general, the earlier the patients undergo the treatment, the better the prognosis will be, and even the effect of curing the disease can be achieved, which not only allows them to survive for 20 years, but also allows them to survive for a long period of time. Individuals are advised to undergo regular medical checkups and to intervene early if they find any abnormal lesions in the colon.