The causes of lymph nodes are varied. If they are caused by inflammation, they can often disappear on their own after the inflammation subsides; if they are caused by malignant lesions, they are usually difficult to disappear. 1. Lymph nodes can disappear on the body surface: Transient lymph nodes caused by inflammatory reaction to the invasion of bacteria and other pathogenic bacteria, often manifested as hyperplasia and enlargement of lymph nodes, which can disappear on the body surface on their own after the inflammatory reaction subsides. Typical example is the enlargement of submandibular lymph nodes that often accompanies colds, but when the cold gets better, the enlarged lymph nodes can no longer be touched. 2. Lymph nodes usually do not fade away: Lymph nodes caused by malignant lesions such as cancer are often difficult to fade away. Typical example is the enlargement of axillary lymph nodes caused by breast cancer. If the cancer cells keep spreading or distant metastasis occurs and the disease is not under control, it is usually difficult for the enlarged and fused lymph nodes to disappear from the body surface completely. Inflammatory lymph nodes may disappear on their own, while lymph node enlargement caused by malignant disease may not disappear on its own.