There are a lot of skin diseases that cause large blisters, such as localized burns, skin allergies, viral infections and autoimmune diseases, all of which can lead to the symptoms of large blisters.
1. Localized burns: such as boiling water burns, can lead to epidermal layer, dermis layer by different degrees of damage, resulting in local tissue metabolic disorders, there can be a leakage of tissue ooze, and then appeared the symptoms of large blisters.
2. Skin allergy: after contact with allergens, can lead to local skin allergic reactions, some patients can appear some larger pustular herpes, looks like large blisters. For example, mosquito bites caused by insect bite dermatitis, papular urticaria, may also be a serious state of dermatitis, eczema.
3. Viral infections: for example, chickenpox-herpes zoster virus infection, which can lead to chickenpox, shingles, etc., which in turn leads to the appearance of blisters of large size on the body surface, accompanied by itching and other symptoms.
4. Autoimmune diseases: such as pemphigus, pemphigoid. Pemphigus occurs in the head and trunk, the blister wall is loose and easy to break, the blister fluid is clarified, itching is not obvious; pemphigus occurs in the trunk and limbs, the blister wall is tense, not easy to break, after the rupture of the vesicle surface oozing blood, accompanied by obvious itching.
The appearance of the above symptoms, should also consider the possibility of other diseases, we recommend that the patient to consult a doctor to confirm the diagnosis, and follow the doctor’s instructions for treatment.