Anaphylaxis is a serious life-threatening systemic multisystemic rapid-onset allergic reaction. Typical anaphylaxis is characterized by rapid onset of itching of the palms, feet and scalp, flushing of the skin, rash and numbness of the mouth and tongue, followed by dyspnea, asthma, laryngeal edema, asphyxia, decreased blood pressure, cardiac arrhythmia, loss of consciousness and shock after medication or food. The earlier the rash and other prodromal symptoms appear, the more serious the prognosis. The main mechanism causing anaphylaxis is that allergens trigger the release of inflammatory mediators such as histamine from concentrated mast cells in human tissues, and these inflammatory mediators can increase vascular permeability and bronchospasm. Thirty-five percent of the fluid in the blood vessels rapidly penetrates into extravascular tissues within 10 minutes, causing skin edema, laryngeal edema, pulmonary edema, and bronchospasm. At the same time, the large amount of fluid infiltration into extravascular also causes a sudden drop in systemic blood volume, causing a drop in blood pressure and circulatory collapse. Drugs are the most common cause of anaphylaxis, common allergenic drugs are: penicillin, sulfonamides, non-steroidal anti-inflammatory drugs, muscle relaxants, radiographic contrast agents and biological agents. In addition, our country in recent years, the Chinese medicine injection preparation induced anaphylaxis significantly increased. Food is another major cause of induced anaphylaxis. The main foods that cause anaphylaxis in our country are: wheat, shrimp, cabbage, celery, cauliflower, bean curd, etc.. Patients usually consume these foods and then exercise can induce severe allergic reactions, which is very dangerous. Fifty percent of deaths from food-induced anaphylaxis die from asphyxia, with most episodes occurring within 30 minutes of eating. There is no cure for anaphylaxis, and there is research being conducted abroad on the desensitization of peanuts and milk, but it has not yet entered clinical use. To prevent anaphylaxis, the first thing is to identify the allergens that cause shock by checking allergens or analyzing medical history in detail, and strictly avoid them in the future life. Once anaphylaxis is triggered by accidental ingestion or misuse, it can be fatal within minutes due to its rapid development. Therefore, people at risk of anaphylaxis need to be equipped with epinephrine medication and injection devices to carry with them, and patients should be educated to save themselves in the first place in case of accidents, which will greatly reduce the mortality rate of anaphylaxis.