Chronic infection of the foot by a nail can be treated by general treatment, medication (penicillin) and surgery. 1. General treatment: patients should pay attention to rest, reduce activities, maintain a regular routine, avoid eating spicy and stimulating food, so as not to aggravate the condition. 2. Drug treatment: chronic infection is usually caused by bacteria, you can use antibiotics for anti-infection treatment, it is recommended to choose the right drug through the drug sensitivity test, commonly used drugs are penicillin, metronidazole, levofloxacin and so on. 3. Surgical treatment: when the infection symptoms are serious and abscesses appear, the abscesses can be drained through surgical incision. It is recommended that the patient consult the doctor for treatment in time, and strictly follow the doctor’s instructions for medication.