If D-dimer is high in late pregnancy, it can be treated by dynamic monitoring and medication. 1. Dynamic monitoring: Pregnant women’s blood is generally in a state of high coagulation in late pregnancy, and D-dimer may be slightly elevated, which is a normal physiological phenomenon; if D-dimer is elevated more obviously, then we should be vigilant against thrombophilia, diabetes, etc. At this time, we should dynamically monitor the changes of D-dimer, so as to timely discover the changes in pregnant women’s body and take therapeutic measures as early as possible. 2. Medication: If D-dimer is elevated significantly, it will easily cause high blood coagulation, and if necessary, low molecular heparin can be used under the guidance of the doctor. It is important to note that pregnant women should ensure adequate nutrition during pregnancy, eat a high nutrient and high protein diet, and exercise appropriately to reduce the risk of blood clots. If there is an abnormal D-dimer test result, it is recommended to consult a doctor in time to clarify the cause of the disease with the help of the doctor and carry out targeted treatment or therapy.