Osteoarthritis of the knee is a chronic joint disease characterized by degeneration of articular cartilage and osteophytes; Professor Yingze Zhang believes that bone loss and osteoporosis are the culprits of the development of osteoarthritis of the knee. The uneven settlement of the tibial plateau due to fibular support is an important factor in the occurrence and development of medial compartment osteoarthritis of the knee joint, thus proposing the theory of uneven settlement of the knee joint, according to which the proximal fibular osteotomy is used to treat patients with medial compartment osteoarthritis of the knee joint with good results. The establishment of the Academic Consortium for Uneven Knee Joint Settlement will relieve the pain of more patients with osteoarthritis and produce greater social benefits.