It is generally safe to take cephalosporin antibiotics after 72 hours of drinking alcohol. The main reason is to avoid a disulfiram-like reaction between alcohol and cephalosporin. It also takes some time for alcohol to be metabolized in the body. Normally it takes 48 hours to 72 hours for alcohol to be completely metabolized in the body. But people with liver and kidney insufficiency may take longer to metabolize it. So for safety reasons, you need to take cephalosporin antibiotics more than 72 hours after drinking. Adjustments can be made according to individual circumstances. In the absence of alcohol consumption, it is safe to use cephalosporin antibiotics as required by the condition, and generally doctors consult the appropriate history of allergies, etc., before using them. Therefore, you need to take the medication under the guidance of your doctor and do not use it without authorization. If you experience any discomfort while taking cephalosporin antibiotics, you need to go to the hospital immediately.