Aortic regurgitation is relatively common in clinical practice, and its incidence, which increases with age, peaks at the age of 40-60 years, with more men than women. A large amount of regurgitation can lead to a decrease in coronary perfusion, which can induce angina pectoris. It has many causes, the acute ones being most commonly bacterial endocarditis, aortic coarctation and blunt chest injury. The most common chronic ones are degenerative lesions, and some are congenital, or caused by dilated aortic roots. In clinical practice, immediate surgical intervention is advocated in acute cases, aortic balloon counterpulsation is contraindicated, and beta-blockers should also be avoided, with a relatively low surgical mortality rate and good long-term results. Patients with chronic massive regurgitation can be asymptomatic and survive for a longer period of time. The key issue is to determine whether the patient needs surgery and the timing of surgery. The timing of surgery is based on the rule of 55, and patients with left ventricular ejection fraction greater than 55% or and end-systolic left ventricular diameter less than 55 mm, without irreversible left ventricular insufficiency, should be operated as early as possible for a better prognosis. Pharmacological treatment is mainly aimed at significantly lowering systolic blood pressure and reducing afterload. Interventional therapy can also be applied, and many aortic valve diseases with severe regurgitation, or massive regurgitation, can be treated with balloon-expandable and self-expandable transcatheter aortic valve stenting. The reduction in coronary flow reserve in patients with aortic regurgitation worsens with increasing regurgitation, and it is traditionally treated with surgery, medications, and in recent years, interventional procedures, especially interventional procedures, which have better prospects in simple aortic regurgitation, aortic valve diastasis, and valve-in-valve procedures.