Small bowel Crohn’s, or small bowel Crohn’s disease, can be detected by small colonoscopy, which reveals localized segmental, asymmetric inflammation. Enteroscopy is mainly used to diagnose colorectal diseases, etc. Crohn’s disease can be diagnosed by colonoscopy biopsy when it involves the terminal ileum. 1. Enteroscopy and small colonoscopy are different examinations. Enteroscopy generally refers to colonoscopy, which can observe the intestinal mucosa of the rectum, sigmoid colon, descending colon, transverse colon, ascending colon, cecum, and up to the end of the ileum, and is used to diagnose colorectal inflammation, benign and malignant tumors, polyps, diverticula, and other diseases. When Crohn’s disease involves the terminal ileum, it can be diagnosed by colonoscopy with biopsy. 2. The indications of small colonoscopy are abdominal pain of unknown cause, diarrhea, small bowel obstruction and gastrointestinal bleeding, etc., which cannot be diagnosed by various other examinations and are highly suspected of small bowel lesions. Small colonoscopy can identify benign and malignant tumors of the small intestine, primary small intestinal lymphoma, small intestinal tuberculosis, Crohn’s disease and so on. 3. Small bowel Crohn’s disease can be found in small bowel microscopy, the presence of segmental, asymmetric inflammation of the mucosa of the small bowel, its characteristic manifestations are mucosal congestion, edema, pseudo-polyps, longitudinal ulcers and pebble-like appearance, and the lesions were jumping distribution. Once diagnosed with Crohn’s disease of the small intestine, patients need to actively cooperate with doctors for standardized treatment.