Treatments for infrapatellar fat pad impingement include manipulative therapy, immobilization therapy, drug therapy, and surgical therapy. Infrapatellar fat pad impingement is mainly due to extreme hyperextension of the knee joint or direct violent impact, so that the fat pad is extruded and causes fat pad congestion, edema and other aseptic inflammatory changes. 1. Manipulation therapy: it can promote local blood circulation, accelerate the absorption of inflammation, loosen adhesion, reduce pain and improve the function of knee joint, including grinding method, pressing and shaking method, pressing method and so on. 2. Immobilization therapy: Acute injuries can be properly braked. The knee joint should be avoided to do extension movements and exercise, and high heels should not be worn when walking to prevent knee hyperextension. 3. Drug therapy: oral non-steroidal anti-inflammatory and analgesic drugs, such as celecoxib, aspirin, etc., can improve local inflammation, reduce edema, pain and other symptoms. It can also be combined with physiotherapy and acupuncture. 4. Surgery: For those who have a clear diagnosis, long term non-surgical treatment and serious impact on joint function, surgery can be performed. The purpose of surgery is to remove part of the excessive fat tissue to restore the normal volume of extra-synovial fat, so that its volume is compatible with the angular conical space. If the diagnosis of infrapatellar fat pad impingement is confirmed, early and standardized treatment is recommended to reduce the adverse effects of the disease. All of the above medications should be used under doctor’s supervision, avoid self-medication.