Oral blistering (blistering) if it is herpes use antiviral drugs, if it is pemphigus use glucocorticoid drugs, if it is caused by hypersensitivity reaction to take anti-allergy drugs. 1. herpes: the oral cavity if herpes localized pinpoint-sized blisters, blisters can destroy the erosion of secondary infections, the treatment of the main use of antiviral drugs, acyclovir, ribavirin. 2. pemphigus: pemphigus can appear in the oral cavity blisters of varying sizes, hand pressure blisters can move easily ruptured, the treatment can use glucocorticoids, immunosuppressants (cyclosporine) and other drugs. 3. Hypersensitivity reaction: when the body contact allergens in the oral cavity can appear rapid development of blisters, blisters can be rapidly enlarged, red, painful and itchy. Treatment mainly stop contact with allergens and take anti-allergy drugs (loratadine). Oral blisters need to go to the hospital to check the cause of the disease, follow the doctor’s prescription medication.