Sudden tingling somewhere in the body may be due to diabetes, shingles, peripheral neuropathy or anxiety and depression. 1. Herpes zoster: lesions are usually distributed along the peripheral nerves. Even with timely treatment, some patients may still have postherpetic neuralgia. 2. Diabetes mellitus: In diabetes mellitus patients, when the lesion involves peripheral nerves, this symptom may also occur, with distal symmetric polyneuropathy being the most representative. 3. Autoimmune peripheral neuropathy: such as Guillain-Barré syndrome, it will be manifested as a sock-like sensation in the fingers or toes, accompanied by numbness and tingling. 4. Anxiety and depression: If the patient is still experiencing tingling sensation even though there are no obvious abnormal results after various examinations, we can consider that it may be a somatization symptom of anxiety and depression. In addition to the above, there are other situations that may lead to the sudden onset of tingling sensation, if the change of lifestyle habits, the symptoms did not reduce, or accompanied by other discomfort, it is recommended to go to the hospital for examination, follow the doctor’s instructions in a timely manner for targeted treatment, so as not to delay the condition.