Cornus officinalis generally has no significant nephrotoxicity when used in the correct dosage, and a physician should be consulted before use. Cornus officinalis has the efficacy of dispersing cold and relieving pain, subduing rebelliousness and stopping vomiting (stopping the upward rush of stomach qi, stopping vomiting), and assisting yang and stopping diarrhea. It is used for treating syncopal headache (headache caused by the invasion of the syncopal meridian), abdominal pain, cold-damp feet (numbness, soreness and swelling of the legs and feet caused by cold-dampness), abdominal pain during menstruation, epigastric distension, acid swallowing (swallowing the acid that goes up to the mouth and throat from the stomach), diarrhea and other conditions. Wu Zhu should not be taken in excess or for a long period of time; it is contraindicated in cases of yin deficiency with heat. It has no obvious nephrotoxicity when used within the scope of indications and according to the correct dosage under the guidance of a Chinese medicine practitioner. Patients need to consult a doctor in a timely manner, under the guidance of a professional physician to standardize the treatment, do not blindly take medication, so as not to cause adverse consequences.