There is a relationship between hypertension and smoking, smoking can increase blood pressure, there may be several mechanisms: 1, smoking can increase the release of norepinephrine from sympathetic nerve endings, which can cause vasoconstriction, thus increasing blood pressure; 2, smoking can impair nitric oxide-mediated vasodilation through oxidative contingency, which can increase the patient’s blood pressure; 3, smoking can cause the patient’s heart rate to increase, pumping blood volume increases, the side pressure on the blood vessel wall The increase in side pressure on the blood vessel wall will raise the patient’s blood pressure; 4. Long-term smoking will make the patient hypoxic, and long-term hypoxia will make the patient vasoconstrict, which will raise the blood pressure. Patients with hypertension are advised to quit smoking, long-term smoking can increase blood pressure and aggravate atherosclerosis in patients causing systemic arteriosclerosis, and complications of hypertension may occur at any time. Patients with hypertension are advised to take regular oral antihypertensive drugs to slow down atherosclerosis and prevent blood pressure fluctuations from causing hypertensive complications.