Escherichia coli is a Gram-negative bacillus, now known as Escherichia coli. Escherichia coli can cause a variety of infections, including urinary tract infections such as urinary tract infections and acute pyelonephritis, acute gastroenteritis caused by eating an unclean diet, and abdominal infections caused after gastrointestinal surgery are also often caused by Escherichia coli. In addition, Escherichia coli can sometimes cause respiratory tract infections, bloodstream infections and other diseases. Because human stool often contains Escherichia coli, coliform counts are often used to determine whether food and water sources are contaminated with bacteria. Treatment of Escherichia coli infection preferred oral quinolone antibiotics, clinically representative drugs such as ciprofloxacin, levofloxacin, etc., can also choose oral cephalosporins such as cefaclor, cefixime, etc., in addition to sulfonamides, tetracyclines for Escherichia coli infection usually also have an effect.