The normal range of ALT125U/L is 0~40U/L, the normal ALT125U/L is more than twice of the upper limit of the normal range, and the elevation of ALT125U/L should be considered to be caused by pathological factors. The normal range of alanine aminotransferase is 0~40U/L, alanine aminotransferase 125U/L is more than twice of the upper limit of the normal range, it is considered that alanine aminotransferase is elevated due to pathologic factors, and it needs to be treated according to the cause of the disease. Physiological factors, such as staying up late, overeating, overwork, etc. can cause transient elevation of aminotransferase, but the degree of elevation is not much, usually not more than twice the normal value. A transaminase of 125 U/L and normal transaminase may be caused by viral hepatitis, cirrhosis, alcoholic hepatitis, fatty liver, liver cancer and other liver diseases. Depending on the cause of the disease, there is a difference in the treatment taken. For example, patients with viral hepatitis need to take antiviral drugs such as entecavir, patients with alcoholic hepatitis need to quit drinking and take liver-protecting treatments such as polyunsaturated phosphatidylcholine, and patients with hepatocellular carcinoma need to undergo surgical treatments. The alanine aminotransferase 125U / L, azalea aminotransferase is normal should go to the hospital in time to improve the examination, to clarify the cause of the disease to give targeted treatment.