Long-term use of aspirin in small doses may have certain adverse reactions, such as gastrointestinal reactions, central nervous system reactions, allergic reactions and bleeding. 1. Gastrointestinal reactions: mainly nausea, vomiting, stomach pain and other gastrointestinal symptoms. 2. Central nervous system reaction: mainly dizziness and headache, tinnitus, hearing loss and so on. 3. Allergic reaction: skin manifestations such as urticaria, red rash, itchy skin, etc.; there may also be bronchospasm allergic reaction, the main symptoms of dyspnea, shortness of breath, asthma and so on. 4. Bleeding: aspirin has an inhibitory effect on platelets, long-term use will increase the risk of bleeding. Aspirin is a drug that inhibits platelet aggregation and is commonly used in clinical practice as a preventive medicine for cardiovascular and cerebrovascular diseases. It is recommended that long-term use of medication should be carried out under the guidance of a doctor, do not take medication without authorization.