Waking up with swollen eyelids in the morning may be caused by drinking too much water before going to bed, or may be caused by angioedema, chalazion and other diseases. 1. Drinking too much water before going to bed: If you consume too much water before going to bed, it may lead to water and sodium retention in the body, resulting in localized edema, which is manifested as swelling of the eyelids when you wake up in the morning. 2. Angioedema: Angioedema may be caused by heredity, food allergy, drugs, physical stimulation and other factors. Patients will show sudden swelling of the skin, and the eyelids will be swollen when waking up in the morning. 3. Chalazion: The formation of chalazion is mainly due to the blockage of the outlet by the secretions of the glands of the blepharoplakia, resulting in retention of secretions. Its causes include chronic conjunctivitis, glandular epithelial hyperkeratosis, and high cholesterol. Patients may present with a lump on the eyelid, swollen and painful eyes, which manifests as waking up with swollen eyelids in the morning. If the patient appears to wake up with swollen eyelids in the morning, when physiological factors are ruled out, he or she can go to a regular hospital and find out the cause of the disease.