When female friends appear in the following 7 situations, they need to consult a doctor in time, because it is often a precursor of infertility. 1, menstrual disorders Changes in menstrual cycle: early or delayed menstruation; changes in menstrual flow: too much or too little menstruation; prolonged menstrual period: common in luteal insufficiency and endometrial inflammation. Amenorrhea: no menstruation at the age of 18 or above; menstruation stops for more than 6 months after menstruation. Amenorrhea causes a lot of infertility. Amenorrhea can be uterine, ovarian, pituitary or hypothalamic according to the location of the lesion. Dysmenorrhea can be caused by endometriosis, pelvic inflammatory disease, uterine fibroids, uterine dysplasia, abnormal uterine position and other diseases. 4. Symptoms before and after menstruation When a series of symptoms such as breast swelling and pain, headache, diarrhea, swelling, fever, mouth and tongue eruption, facial acne, menstrual depression or irritability occur periodically before and after menstruation of a minority of women, they are mostly due to endocrine disorders or abnormalities of luteal function, which can lead to infertility. 5, abnormal leukorrhea when there is leukorrhea increase, yellow color, smell, tofu dregs or watery, or with vulvar itching, pain and other symptoms, may be due to vaginitis, cervicitis, endometritis, adnexitis, pelvic inflammatory disease and a variety of sexually transmitted diseases, which in turn can affect the degree of conception. 6, abdominal pain Chronic lower abdominal pain, abdominal pain or lumbosacral pain is often due to pelvic inflammatory disease, uterine inflammation, ovarian inflammation, endometriosis or uterine and ovarian tumors and other diseases, and these diseases often lead to infertility. 7.Milk overflow Non-lactating female breasts on their own or after extrusion of milk overflow, more suggestive of hypothalamic insufficiency, pituitary tumors, prolactinomas or primary hypothyroidism, chronic renal failure and other diseases, which can lead to infertility.