Clear blisters on legs may be associated with causes such as shingles on legs, papular urticaria, and traumatic burns. 1. Herpes zoster: when infected with varicella-zoster virus, it causes herpes zoster on legs. Symptoms such as erythema, papules and clustered blisters appear along with pain. It can be treated with oral medications such as vasiclovir tablets and topical creams such as acyclovir cream under a doctor’s supervision. 2. Pemphigus urticaria: After being bitten by mosquitoes, pemphigus urticaria can be formed, and symptoms mainly manifested by erythema, papules and pimples will appear on the legs. Particularly after scratching, a rash may appear and be accompanied by severe itching. Under the guidance of a doctor, you can either take oral medication such as loratadine or apply ointment such as Dinaid cream. 3. Traumatic burns: For example, when a heater or hot water bag burns the legs, it can cause blisters in addition to severe pain. Therefore, for transparent blisters on the legs, it is recommended to go to a regular hospital for examination and clinical treatment under the guidance of the doctor.