If a patient has liver disease, he or she will generally experience weakness, as well as nausea and vomiting in some patients. In addition, for some liver diseases, such as the acute stage of viral hepatitis, the bilirubin in the body will be further increased due to the necrosis of liver cells in the liver. If the total bilirubin in the body is elevated above 34.2 μmol/L, the patient is most often considered to have jaundice. In patients with jaundice, it is necessary to further determine whether the jaundice is due to an obstructive cause or to hepatocellular necrosis. Generally, in patients with viral hepatitis, in the acute phase, most of the bilirubin is elevated due to hepatocyte necrosis, mainly due to elevated indirect bilirubin. In this case, the patient needs to find out the cause of the liver disease, whether it is caused by viral hepatitis or autoimmune hepatitis, or by other diseases of the liver, such as tumor diseases of the liver. The patient will need to have blood tests for liver function, ultrasound or CT of the upper abdomen, and if necessary, routine blood tests and coagulation. Several of these tests will initially screen the patient for the cause of the disease. In the case of viral hepatitis, the hepatitis B tri-system and hepatitis C antibodies, as well as further tests for hepatitis B DNA and hepatitis C RNA are also needed, and the next step of treatment will be considered based on the test results.