Donepezil Hydrochloride Tablets are cholinesterase inhibiting drugs that are often used starting at 5mg/day and gradually increasing to 10mg/day, taken orally at bedtime, for improving mild to moderate Alzheimer’s symptoms. Specific usage is as follows: The initial therapeutic dose for adults and the elderly is 5mg/dose (as donepezil hydrochloride) once a day, taken orally at night before bedtime. The 5 mg/day dose should be maintained for at least one month to evaluate the patient’s clinical response, and the steady-state blood concentration of donepezil hydrochloride achieved. After one month of treatment at a therapeutic dose of 5 mg/day, the dose of donepezil hydrochloride may be increased to 10 mg/day (as donepezil hydrochloride) taken orally once a day at bedtime if the patient’s results are poor. In patients with renal insufficiency, donepezil hydrochloride should be taken similarly to normal as its clearance is not affected by this. For patients with mild to moderate hepatic insufficiency, it is recommended that the dose be adjusted appropriately according to individual tolerance; there is no clinical information on the use of the drug in patients with severe hepatic insufficiency. Donepezil hydrochloride is contraindicated in pregnant women. This preparation contains lactose and is contraindicated in patients with lactose intolerance, glucose-galactose malabsorption and other rare genetic disorders. It is contraindicated in persons with a history of hypersensitivity to donepezil hydrochloride, piperidine derivatives or excipients in the preparation. In summary, the use of donepezil hydrochloride must be under the guidance of a professional physician reasonable use of medication, do not unauthorized use of medication. I hope the above answer is helpful to you.