Myocardial infarction can occur even when blood pressure and lipids are normal. Myocardial infarction mainly occurs on the basis of coronary atherosclerosis, and hypertension and hyperlipidemia are one of the common causes of coronary atherosclerosis. However, there are many other causes of coronary heart disease, such as increasing age, long-term smoking and drinking, and abnormal blood sugar. Patients who do not have hypertension and hyperlipidemia are still at risk of developing coronary artery disease. Coronary atherosclerosis is the basis for the development of coronary heart disease, and hardening occurs with increasing age. Smoking and drinking, abnormal blood sugar, abnormal blood lipids, and high blood pressure all increase the risk of atherosclerosis. The occurrence of atherosclerosis is multifactorial, not caused by a specific factor. Patients with normal blood lipids and blood pressure should also assess the risk of coronary heart disease, pay attention to the control of various risk factors, and if necessary, give treatment under the guidance of a doctor.