Abnormal blood creatinine may be a normal physiological phenomenon, such as muscular athletes, eating a lot of meat, etc.; it may also be a pathological phenomenon, such as acute and chronic renal failure, which requires standardized treatment according to medical advice. Generally speaking, the normal level of blood creatinine is 53~106μmol/L for men and 44~97μmol/L for women, and the standard value is different from hospital to hospital, so you can check the reference value according to your local hospital. Abnormal blood creatinine needs to consider physiological reasons, common causes such as muscular athletes, strenuous exercise, eating a large amount of high-protein food, etc. At this time, there is no need for special treatment, pay attention to rest, eat a light diet, and regular review can be. In addition, we can not exclude the possibility of pathological factors, such as diarrhea, urinary tract obstruction, acute renal failure due to heart failure, chronic pyelonephritis, chronic interstitial nephritis, hyperuricemia due to renal damage, etc., the cause of the disease is unclear, if necessary, can be perfected by renal puncture biopsy, to clarify the type of pathology, and follow the doctor’s instructions for treatment. Patients with abnormal blood creatinine are advised to go to regular hospitals in time and receive standardized treatment under the guidance of physicians.