There is no such clinical term; male gigantism refers to a condition of precocious male development, not to the size of the penis. Macrocephaly is a clinical manifestation of congenital adrenal hyperplasia, also known as adrenogenital syndrome or adrenal sexual dysphoria. It is mainly due to defects in the biosynthesis of adrenocorticotropic hormone and the lack of enzymes necessary for its synthesis, resulting in abnormal synthesis of corticotropin, which leads to the emergence of this disease. In most cases, the adrenal glands do not produce enough glucagon and saline hormones, but produce too many androgens, resulting in different degrees of hypoadrenocorticism, which is usually characterized by masculinization in girls and precocious puberty in boys, as well as hyponatremia and hypertension. Therefore, patients with macrosomia should go to the hospital in time for consultation and early treatment after identifying the cause of the disease.