What to do if interferon causes thrombocytopenia

Interferon causes thrombocytopenia generally according to the degree of platelet reduction can be divided into four levels, need to take different methods to alleviate the different degree of reduction caused by playing interferon. 1.Grade 1: platelet value is (75~100)×10^9/L. In this case, the decrease of platelet is a mild decrease, which has less effect on the coagulation function of the body and basically will not cause bleeding, so there is no need for special treatment, and only need to pay attention to monitoring the change of platelet, and continue to follow the original dosage of interferon and the frequency of medication. 2. Level 2: If the platelet value is (50~75)×10^9/L, you can consider taking Ricodin capsules to improve the platelet count, so as not to cause a significant decline in coagulation function. At the same time, it is also necessary to monitor whether there is a continuing trend of platelet decline, if there is a continuing trend of decline, it is necessary to reduce the dose of interferon or reduce the frequency of use. 3.Grade 3: Platelet count is (25~50)×10^9/L, which indicates that the coagulation function of the body has been significantly affected, and it is necessary to pay close attention to the skin and mucous membranes for bleeding, and closely monitor the platelet count, and reduce the dose or frequency of interferon. 4. Grade 4: Platelet count is lower than 25×10^9/L. This is a more serious condition, which has already formed coagulation dysfunction and is likely to cause bleeding, and interferon must be discontinued immediately. Consider using hormones (prednisone) or interleukin-11 to raise the platelet count, or a single platelet transfusion may be indicated. Interferon-induced platelet lowering is usually transient and can return to the original platelet count at the end of treatment. In general, patients can adjust their medication in a timely manner as prescribed by the doctor.