With the development of modern time biomedicine, the synchronous relationship between human and natural time rhythm has been confirmed by conclusive facts. The recognition of Chinese time medicine by the world can be traced back to 1984, when Wu Jinyi from Sichuan represented China to attend the International Symposium on Time Medicine, revealing to the world the remarkable insight of our ancient sages who looked up to the sky and down to the earth, taking the body from near and the things from far, and the holistic view of heaven and man, which made the participants very amazed by the foresight of ancient Chinese time medicine. Chinese time medicine includes the doctrine of luck, the Ziwu flow injection needle method, the eight methods of the spiritual tortoise, the eight methods of flying, etc., of which the most representative is the Ziwu flow injection needle method. This acupuncture method has been proven through thousands of years of clinical practice to be a perfect and unique therapeutic method, with significant scientific value and practical value. Jinan Traditional Chinese Medicine Hospital Acupuncture and Moxibustion Department Wan Hongming The Ziwu flow injection acupuncture method is based on the sixty-six five infusion points below the elbow and knee of the twelve meridians, combining the meridian points with the five elements of yin and yang and the sun and the time, using the changes of the five elements of yin and yang to project the opening and closing of the body’s qi and the corresponding meridian points, grasping the time to open the points on time, and applying acupuncture with the opening and closing of its qi and blood. For some difficult and chronic diseases, it is often as effective as a rafter. It has the advantages of safe needle application, wide range of application, applicable to many types of diseases, short treatment course, significant effect, etc. It is a better clinical treatment means. Since we started the Ziwu Liujiao acupuncture method and the eight methods of Linggui, we have had remarkable effects on headaches, insomnia, stomach pain, joint pain, stroke and many other diseases. Especially for the various diseases with obvious time attack pattern, using this theory to identify and treat the evidence, we have been able to achieve miraculous results every time.