Eardrum collapse refers to tympanic membrane invagination. In patients with tympanic membrane invagination, there may be hearing loss, congestion, tinnitus, and other discomfort. In such patients, the tympanic membrane is usually found to be inside-out, the light cone is shortened or disappeared, the tympanic membrane is not clearly marked, and there may be air bubble shadow or air-fluid plane inside the tympanic chamber. For the treatment of this disease, a combination of nasal spray hormone, antihistamine nasal spray, short-term application of antibiotics, and oral hormone if necessary are mainly used in clinical practice. However, patients with recurrent secretory otitis media, especially middle-aged and elderly patients with unilateral occurrence, should be vigilant. Some patients, such as early stage of nasopharyngeal carcinoma, have symptoms of secretory otitis media, so we must be vigilant for such patients. It is recommended to check electronic nasopharyngoscopy to rule out the possibility of new organisms in the nasopharynx.