Urine leukocytes (++++) are most often caused by urinary tract infections or acute pyelonephritis, mostly accompanied by frequent urination, urinary urgency, painful urination or lumbago, chills, high fever and other manifestations of inflammation and infection. In this case, treatment is often required, and quinolones or cephalosporin antibiotics can be chosen empirically to treat the condition, as the most common cause of urinary tract infections is E. coli infection. In addition to these medications, it is also important to drink more water, urinate more often, and prevent bacterial colonization. Drinking more than 2,000 ml of water per day can effectively flush the urethra and avoid bacterial colonization. The course of antibiotics is still divided mainly according to the site of infection. The course of treatment for cystitis is 5-7 days, and the course of treatment for acute pyelonephritis should reach 2 weeks, so that the recurrence of the disease can be prevented.