Antihypertensive drugs suitable for long-term use with fewer side effects include calcium channel antagonists, B-blockers, and angiotensin-converting enzyme inhibitors. Calcium channel antagonists such as verapamil and nifedipine can lower blood pressure by reducing vasoconstriction; B-blockers such as bisoprolol and metoprolol; and angiotensin-converting enzyme inhibitors such as captopril and enalapril dilate blood vessels by inhibiting the formation of angiotensin. In addition to the above drugs, angiotensin 2 receptor blockers such as valsartan, chlorosartan and other drugs also have significant antihypertensive drugs and have less side effects. Due to individual differences, the drug does not have the absolute most effective, you need to choose the most suitable for their own medication under the advice of the doctor, the occurrence of adverse reactions need to consult a doctor in a timely manner, drug allergy is prohibited.