The seminal fructose in male semen is mainly a liquid component produced by the seminal vesicle gland, which produces seminal fructose to energize sperm after entering the female birth canal, and allows sperm to travel normally in the female birth canal. Therefore, the factors that cause low seminal plasma fructose include the production of seminal plasma fructose and the process of sperm excretion into the birth canal. In men, low seminal plasma fructose may be caused by infectious inflammation. In women with vaginitis or men with inflammation of the genitourinary system, the process of sperm ejaculation may be interfered with by inflammatory factors, leading to a decrease in seminal plasma fructose capacity. There is also due to congenital testicular insufficiency, such as endocrine dysfunction to produce hormone levels, which can lead to a decrease in seminal plasma fructose production, it is recommended to check if there is congenital testicular insufficiency.